In February, a team of researchers published a paper in the Journal of Cosmetic Dermatology to analyze the different injection techniques that are popular with Qwo. This injectable used to vanquish cellulite for up to two years quickly became one of the most-requested at Palo Alto Laser and Skin Care during the summer months. However, autumn and winter are great seasons for this procedure (since it’s easier to hide the temporary bruising in the treated area outside of swimsuit seasons), making right now the perfect time to see what researchers have to say about this revolutionary procedure.

Although Qwo is currently only FDA-approved to treat cellulite in women’s buttocks, the research team took a look at using this treatment in both the buttocks and thighs, noting that “Given difference in buttock versus thigh cellulite, collagenase clostridium histolyticum-aaes [Qwo] injection technique may impact treatment effects at this site.” Many people, including those in the skin care industry, are hopeful that Qwo will be approved for additional uses in the future, making this paper especially exciting.

Qwo, It’s You!

An open-label trial welcomed women who had cellulite of all severities and degrees on their buttocks and/or thighs. During the testing, Qwo was administered as 12 injections into each of the buttocks or thighs for a total dose of 1.68 mg. This occurred three times in total, 21 days apart, which is in keeping with how Qwo should be administered. During the first treatment, the subjects were split into five groups. Group A received shallow injections with 3 aliquots (doses), Group B received a shallow injection with 1 aliquot, Group C received a deep injection with 1 aliquot, Group D received both deep and shallow injection with 5 aliquots, and Group E received shallow injections with 4 aliquots. At day 71, the Severity Scale depression depth was assessed and safety was evaluated.

It was discovered that Group A enjoyed the biggest baseline-adjusted improvement when it came to treating the buttocks. Group D showed the best improvement for thigh injections. In regards to “safety,” which largely includes occurrence and severity of bruising, Groups A, D, and E were the most favorable. The researchers concluded that different Qwo injection techniques are required for treating the buttocks versus the thighs.

The Rise of Qwo

Qwo initially presented with great safety and efficacy scores in its phase 2 and phase 3 trials (before receiving FDA approval). Then (and now), using Qwo in the thighs remains investigational. Qwo works by releasing the septae, the fibers that create a matrix that fat pushes through, which creates the appearance of cellulite. Thus, Qwo can smooth the skin’s surface—and in turn seriously boosts confidence. However, the anatomical makeup of the buttocks and thigh is very different, including the cellulite in these areas.

It looks like there is still a ways to go before Qwo can be approved for cellulite treatment in areas beyond women’s buttocks, but the findings are hopeful. It is a good reminder of why Qwo is not just administered anywhere and that the unique features of different parts of the body respond differently to treatments. Also keep in mind that while losing weight probably isn’t going to get rid of your cellulite entirely, it can be helpful. If you have cellulite in the thighs or an area not treatable by Qwo (yet), there are options.

Combining Treatments

Qwo pairs wonderfully with CoolSculpting, the longstanding option to freeze away fat with no needles and no downtime. CoolSculpting uses cryolipolysis to target small areas of unwanted fat, requiring 3 – 6 sessions on average for optimal results. The “killed” fat is then naturally absorbed, metabolized, and eradicated by the body in the months following the treatment. It’s a means of spot reduction that you can’t achieve with diet and exercise alone, and can be a great tool in helping minimize the appearance of cellulite in the thighs, arms, and other areas.

If you would like to find out more about Qwo and other body contouring methods available in-office, schedule a consultation today. Contact Palo Alto Laser and Skin Care now by calling the office, or for the quickest response complete the online contact form.